Digitalis | Digoxin M O A & Role in Congestive Heart Failure

#medicines #drnajeeb #pharmacology #medicaleducation #drnajeeblectures #cardiology
Digitalis | Digoxin M O A & Role in Congestive Heart Failure
Like this video? Sign up now on our website at www.DrNajeebLectures.com
to access 800+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM CZcams). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $45 ONLY!
Sign up now on our website at members.drnajeeblectures.com/...
---------------------------------------------------------------------------------------------------------------------------
Why sign up for premium membership? Here's why!
Membership Features for premium website members.
1. More than 800+ Medical Lectures.
2. Basic Medical Sciences & Clinical Medicine.
3. Mobile-friendly interface with android and iOS apps.
4. English subtitles and new videos every week.
5. Download option for offline video playback.
6. Fanatic customer support and that's 24/7.
7. Fast video playback option to learn faster.
8. Trusted by over 2M+ students in 190 countries.
---------------------------------------------------------------------------------------------------------------------------
The main mechanism of action of digitalis is on the sodium-potassium ATPase of the myocyte. It reversibly inhibits the ATPase resulting in increased intracellular sodium levels. The build-up of intracellular sodium leads to a shift of sodium extracellularly through another channel in exchange for calcium ions
The principal pharmacodynamic property of digitalis is its ability to increase the force of systolic contraction. All other cardiovascular responses are considered to be secondary to the increase in myocardial contraction
Digoxin binds to and inhibits the sodium/potassium-ATPase (sodium pump) within the plasma membrane of cardiac myocytes. This inhibition increases the intracellular sodium content which in turn increases the intracellular calcium content which leads to increased cardiac contractility
---------------------------------------------------------------------------------------------------------------------------
Join this channel to get access to perks:
Sign up now on our website at members.drnajeeblectures.com/...
/ @doctornajeeb
Follow us on Facebook :- / drnajeeb
Follow us on Instagram :- / drnajeeblectures

[@chiragnichiragni6169]

Thank you so much sir. I am always surprised that how you describes every topic in such a beautiful way. Bless to have such a talented teacher like you.

[@DoctorNajeeb]

So nice of you

[@becherkapuka1405]

Thanks Doc ❤

[@user-yl5xd9mg1r]

Watching from Tanzania 😊😊😊 I always find my smile when watching your videos. Thanks so much Dr

[@DoctorNajeeb]

You are so welcome 🤗

[@dipanwitabiswas1605]

You're the best teacher sir...

[@salmanahmad1853]

Great 💞 SIR

[@sundaramoorthdi1265]

Very interesting Lecture on heart failure and its pharmacotherapy.Thanks sir.

[@DoctorNajeeb]

It's my pleasure❤

[@saktimanpanda1284]

Sir my life will become a heaven if you reply to my comment.... Lots of love to you sir.. From India

[@DoctorNajeeb]

You made me smile. Stay blessed and very happy. ❤️

[@muhammadsazzad5509]

The lecture is very easy to understand ❤

[@DoctorNajeeb]

Glad to hear that❤

[@mrrishiraj88]

Good day greetings, Sir

[@DoctorNajeeb]

Thank you❤

[@Ali_Shaikh.1M]

Excellent ❤

[@DoctorNajeeb]

Glad you like it!❤

[@lujjobamesusera6718]

Excellent Dr

[@DoctorNajeeb]

Thanks a lot❤

[@solomonkissiboamah8314]

Well done Doctor watching from Ghana west Africa 🌍

[@niteshb4195]

Please put videos neural reflex

[@varunkashyap7106]

Sir evening nice lecture❤

[@DoctorNajeeb]

Thank you❤

[@KarthiKeyan-dr4pq]

Greetings sir
Sir a hypothetical question
What hapeens when we give digoxin begore compensatory mechanism

[@KarthiKeyan-dr4pq]

Sir please reply sir🙏

[@Garin-Rijiya]

Mashaa Allah. May Allah bless you