Is drinking milk a Superpower? Genetic Mutations: Crash Course Biology #37

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  • čas přidán 22. 05. 2024
  • Science fiction is full of superpowered mutants, but in reality, mutations are much more diverse and complex. Sometimes, they can change someone’s entire body, and other times, we don’t notice them at all! In this episode, we’ll unpack what mutations are, how they work (including substitutions and frameshift mutations), and how scientists are learning to control mutations using tools like CRISPR/Cas9 and gene therapy.
    Introduction: Mutations Outside the Movies 00:00
    What Are Mutations? 1:20
    What Determines Mutations' Effects? 3:10
    Types of Mutations 4:16
    Positive, Negative, or Neutral? 7:43
    Gene Therapy & CRISPR 8:23
    Pharmacogenomics 10:59
    Review & Credits 11:58
    This series was produced in collaboration with HHMI BioInteractive, committed to empowering educators and inspiring students with engaging, accessible, and quality classroom resources. Visit BioInteractive.org/CrashCourse for more information.
    Check out our Biology playlist here: • Biology
    Watch this series in Spanish on our Crash Course en Español channel here: • Crash Course Biología
    Sources: docs.google.com/document/d/1G...
    ***
    Crash Course is on Patreon! You can support us directly by signing up at / crashcourse
    Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever:
    Leah H., David Fanska, Andrew Woods, DL Singfield, Ken Davidian, Stephen Akuffo, Toni Miles, Steve Segreto, Kyle & Katherine Callahan, Laurel Stevens, Burt Humburg, Perry Joyce, Scott Harrison, Mark & Susan Billian, Alan Bridgeman, Breanna Bosso, Matt Curls, Jennifer Killen, Jon Allen, Sarah & Nathan Catchings, team dorsey, Bernardo Garza, Trevin Beattie, Eric Koslow, Indija-ka Siriwardena, Jason Rostoker, Siobhán, Ken Penttinen, Nathan Taylor, Barrett & Laura Nuzum, Les Aker, William McGraw, Vaso, ClareG, Rizwan Kassim, Constance Urist, Alex Hackman, Pineapples of Solidarity, Katie Dean, Stephen McCandless, Wai Jack Sin, Ian Dundore, Caleb Weeks
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Komentáře • 39

  • @samstromberg5593
    @samstromberg5593 Před měsícem +31

    I haven’t been here in a while so I’ve only ever seen Hank Green (I think that’s his name?) do these but oh my gosh this guy is gold

  • @Velvetynailworld
    @Velvetynailworld Před měsícem +7

    My kids and I watch only these biology videos. You’re such an amazing teacher and one of the more engaging ones for sure.

  • @AlienBemular
    @AlienBemular Před měsícem +40

    There's a character named Bone from One punch man who gets Durability from drinking a lot of milk.

  • @johndillinger6563
    @johndillinger6563 Před měsícem +25

    I'll take the well rested mutation if I have a choice. 😁

  • @mickmash13
    @mickmash13 Před měsícem +19

    I have hypermobile EDS, which is a mutation in how my body produces connective tissue. But there are other types that can affect other systems in the body. There's even a lot of variation in how severe hEDS is. I'd be curious to see the genetic variations between various types of EDS and the severity of EDS symptoms.

  • @angiepen
    @angiepen Před měsícem +11

    Yet another example of how awesome Dr. Sammy is. Hopefully he's already set up to do a Crash Course Entomology some time in the near future. :)

  • @williambilyeu9801
    @williambilyeu9801 Před měsícem +19

    Dr. Sammy calling for his super suit remind me a Freezone from "The Incredibles." 😊😅😂

  • @phoenixaasted
    @phoenixaasted Před měsícem +11

    Dubious food from legend of Zelda 1:58

  • @suvikhyasiingh6073
    @suvikhyasiingh6073 Před měsícem +14

    we also have a gene named sonic hedgehog which is an essential part of embryonic development.

  • @Aki-yq9bw
    @Aki-yq9bw Před měsícem +6

    Great video as always! Thank you!

  • @asiaeve4066
    @asiaeve4066 Před měsícem +5

    So interesting! Makes me miss biology lol I may take a college class in it senior year 😋🧬✨

  • @johnm3066
    @johnm3066 Před měsícem +2

    Crazy how our bodies cells and genes resemble a computer program, i.e data structure or algorithm.

  • @abramisme
    @abramisme Před měsícem +3

    nice! thank you for all you do! keep it up!

  • @dreamcatcher5502
    @dreamcatcher5502 Před měsícem +1

    Amazing !! Can you make a video explaing the MTHFR gene mutation please ? I carry 2 coppies and it has caused me a lot of problems over my life. Thank you for all your work !! ❤

  • @hassenfepher
    @hassenfepher Před měsícem +1

    Fyi. Eating ice cream from the carton while watching this. Super power!!!

  • @gamerkid2759
    @gamerkid2759 Před měsícem +4

    Good video!

  • @b1laxson
    @b1laxson Před měsícem +1

    It is important to know your family medical history like parent and grand parents. The "mutations" they had are more likely to be ones you have. Knowing what they had to avoid or benefit from is good for yourself. For example there are some at risk of addiction affects so should just never start.

  • @Caterfree10
    @Caterfree10 Před měsícem +1

    The reason I remember the ACTG letters is bc of GCAT in Homestuck lol. Useless info for me given I’m not exactly a geneticist but hey, it’s a good memory device anyway.

  • @Davlavi
    @Davlavi Před měsícem +1

    Very cool thanks.

  • @kmcsciguy
    @kmcsciguy Před měsícem

    Excellent video covering mutations and the details!

  • @pedrostormrage
    @pedrostormrage Před měsícem

    6:22 "There's a chance that these 'silent mutations' aren't so silent at all" Yeah, a few important factors here are codon optimality (changing a codon can slow down protein production even if codes for the same aminoacid), mRNA structure (changes in the mRNA sequence affect its folding pattern, which in turn affects interaction with other proteins or how efficiently it's translated), and splicing (they can create or destroy splice sites, changing the final mRNA).

  • @user-pk4hn1uz1k
    @user-pk4hn1uz1k Před měsícem

    thanks, please update the playlist

  • @gailaltschwager7377
    @gailaltschwager7377 Před měsícem

    Thank you!

  • @johnadams3802
    @johnadams3802 Před měsícem

    "Where is my supersuit?"
    I've been asking that question since I was a kid.

  • @turtletom8383
    @turtletom8383 Před měsícem

    Have y'all done one on horizontal gene transfer. If not please do.

  • @mymechanicfriend6017
    @mymechanicfriend6017 Před měsícem

    Great Work ✊🏾☝🏾🔥📖📠

  • @MarcLeitermann
    @MarcLeitermann Před měsícem

    Fantastic presenter!

  • @Caterfree10
    @Caterfree10 Před měsícem +1

    STATIC SHOCK LOVE HELL YEAH

  • @MrMetro-mt5qv
    @MrMetro-mt5qv Před měsícem +5

    I want the mutant ability to teleport.

  • @kmcsciguy
    @kmcsciguy Před měsícem

    I saw that “dubious food” reference

  • @sidhantvarshney4185
    @sidhantvarshney4185 Před měsícem +3

    Yaaay I'm a mutant......which I already knew tho 😅

  • @Speed001
    @Speed001 Před měsícem

    Cool

  • @rayfwu
    @rayfwu Před měsícem

    I have a mutation where I don't get armpit or foot odor.

  • @malkum77ify
    @malkum77ify Před měsícem +2

    To me my X-Men!

  • @dillonqaphsiel7977
    @dillonqaphsiel7977 Před měsícem +1

    Based

  • @malkum77ify
    @malkum77ify Před měsícem +1

    You should have used the X-Men animated series theme music! LOL

  • @andrew24601
    @andrew24601 Před měsícem +5

    I’m so happy that you chose a queer black person to host this series 💕 It makes me feel welcome in STEM

  • @LeandroFTW
    @LeandroFTW Před měsícem +1

    I can destroy milk and hot foods.

  • @Mojud_Zikr
    @Mojud_Zikr Před měsícem +5

    After knowing the seriousness of Climate change and reading many philosophers & religions, I guess, we need to become Vegan asap. It's already too late.