BUN Test/Urea: Role in Kidney function Testing- Conditions with High Blood Urea Nitrogen- Dr Kasi MD

#BUN #Urea
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BUN Normal range : 7 to 20 mg/dL (2.5 to 7.1mmol/L)
Urea : 20 to 40 mg/dL
Testing preparation : No special preparation needed
Sample: Venous Blood
What is BUN ?
Blood Urea Nitrogen (BUN) is an abbreviated form of BUN. It is one of the most common test ordered to assess the renal function.
Nitrogen in the body is present in proteins and Nucleic acids. The only non protein nitrogen substances present in the body are urea and ammonia.
How is BUN different from urea?
BUN is an integral component of urea . Catabolism of proteins result in the formation of urea. (NH2-CO-NH2) Estimation of the nitrogen component of urea is called as BUN . Both Urea and Urea nitrogen are interpreted in the same manner.
How is it formed
BUN/ Urea is formed in the liver as products of urea cycle. During the catabolism of the proteins, the nitrogen present in the proteins is captured initially in the form of ammonia (NH3). Since ammonia is dangerous , it is bound to be transported to the liver and converted into urea. The urea formed is eventually excreted in urine (90 %) and the rest through Gastrointestinal tract and skin.
Background score courtesy
"Carefree" Kevin MacLeod (www.incompetech.com)
incompetech.co...
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[@v2kmagic007]

Nice work
Thanks