Carbon Dioxide Transport | Respiration & Gas Exchange | Part 1/6
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- čas přidán 6. 09. 2024
- #CO2Transport #CarbondioxideTransport #GasExchange #Respiration
Carbon Dioxide Transport | Respiration & Gas Exchange | Part 1/6
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Carbaminohemoglobin (or carbaminohaemoglobin, also known as carbhemoglobin and carbohemoglobin) is a compound of hemoglobin and carbon dioxide, and is one of the forms in which carbon dioxide exists in the blood. Twenty-three percent of carbon dioxide is carried in blood this way (70% is converted into bicarbonate by carbonic anhydrase and then carried in plasma, 7% carried as free CO2, dissolved in plasma)
When carbon dioxide binds to hemoglobin, carbaminohemoglobin is formed, lowering hemoglobin's affinity for oxygen via the Bohr effect. The reaction is formed between a carbon dioxide molecule and an amino residue. In the absence of oxygen, unbound hemoglobin molecules have a greater chance of becoming carbaminohemoglobin. The Haldane effect relates to the increased affinity of de-oxygenated hemoglobin for H+: offloading of oxygen to the tissues thus results in increased affinity of the hemoglobin for carbon dioxide, and H+, which the body wants to get rid of, which can then be transported to the lung for removal. Because the formation of this compound generates hydrogen ions, haemoglobin is needed to buffer it.
Hemoglobin can bind to four molecules of carbon dioxide. The carbon dioxide molecules form a carbamate with the four terminal-amine groups of the four protein chains in the deoxy form of the molecule. Thus, one hemoglobin molecule can transport four carbon dioxide molecules back to the lungs, where they are released when the molecule changes back to the oxyhemoglobin form.
In physiology, respiration is the movement of oxygen from the outside environment to the cells within tissues, and the removal of carbon dioxide in the opposite direction.
The physiological definition of respiration differs from the biochemical definition, which refers to a metabolic process by which an organism obtains energy (in the form of ATP and NADPH) by oxidizing nutrients and releasing waste products. Although physiologic respiration is necessary to sustain cellular respiration and thus life in animals, the processes are distinct: cellular respiration takes place in individual cells of the organism, while physiologic respiration concerns the diffusion and transport of metabolites between the organism and the external environment.
Gas exchanges in the lung occurs by ventilation and perfusion. Ventilation refers to the in and out movement of air of the lungs and perfusion is the circulation of blood in the pulmonary capillaries. In mammals, physiological respiration involves respiratory cycles of inhaled and exhaled breaths. Inhalation (breathing in) is usually an active movement that brings air into the lungs where the process of gas exchange takes place between the air in the alveoli and the blood in the pulmonary capillaries. Contraction of the diaphragm muscle cause a pressure variation, which is equal to the pressures caused by elastic, resistive and inertial components of the respiratory system. In contrast, exhalation (breathing out) is usually a passive process.
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Dear Dr Najeep. Thank you for powerful lectures but I would like to implicate these. 1. O2 delivery is about 1000 ml but use of 02 250 ml. 2 Carbohydrates alredy have H20. Thank you
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C6H12O6+6O2=6CO2+6H2O...There is O2 and CO2 also equal in quantity n why is it possible...250mlO2=200mlCO2?
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im in school i got this question right omg its obviouse ofc glucose and oxygen ----> co2 hzo and energy duuuuh
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should be 300 ml of oxygen so that the maths make sense, right?
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Co2 is a waste. It must go out to our body
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