Respiratory Response To High Altitude | Acclimatization Physiology | Respiratory Physiology
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- čas přidán 23. 07. 2024
- ✨High Altitude Physiology is quite complex. In this video I've made an attempt to briefly summarise and explain some of the changes that happen with focus on points that are usually needed for the USMLE Step 1. I hope it helps you with studying! 😊
🔢 The numbers used in this video are only to illustrate the reduction in barometric pressure and so, oxygen for explanation purposes.
🌟What's in this video?
0:00 - Intro
0:27 - Changes in inspired air
1:18 - Changes in Ventilation (O2, CO2, Chemoreceptors)
3:55 - Changes in Circulation (Hypoxia Inducible Factors, Erythropoietin)
5:21 - Changes in tissues (Oxygen Dissociation Curve)
5:47 - Hypoxic Vasoconstriction
✨ Other videos you may need :
🔅Gas Exchange Principles: • Gas Exchange Principle...
🔅Oxygen Hemoglobin Dissociation Curve: • Oxygen Hemoglobin Diss...
🔅Respiratory Regulation | Part 1 | Centres of Respiration:
• Respiratory Regulation...
🔅Respiratory Regulation | Part 2 | Chemoreceptors : • Respiratory Regulation...
🔅Respiratory Response to Exercise: • Respiratory Response T...
💫 For more videos like this, subscribe to my channel!
Byte Size Med: / @bytesizemed
📚Factual References & for Further Reading:
- Guyton and Hall Textbook of Medical Physiology
- Gray’s Anatomy for Students
- Ganong’s Review of Medical Physiology
- Costanzo’s Textbook of Physiology
- First Aid for the USMLE, 2020 edition
- Openstax Anatomy and Physiology
openstax.org/details/books/an...
- Openstax Biology
openstax.org/details/books/bi...
(The last two are links to open-source references. They are NOT affiliate links)
🌤 Note:
These are just a collection of my notes. So use them the way you would use borrowed notes from a friend. 📝
The images in this video are hand-drawn for illustration and explanation only.✍️ Hence, they may not be anatomically accurate. I am just one person making these videos. If there are any errors, that is unintentional. I try super hard to avoid them. Please let me know if you find any, so it gets clarified for other viewers. Science constantly evolves and changes. New discoveries are made everyday. So some of the information in these videos may become outdated. If you notice that, please let me know so I can update them.
⚡️Disclaimer:
These videos are NOT a substitute for a medical textbook. Textbooks are written by experts (which I do not claim to be), edited, proofread and referenced. Please use them.
The information has been sourced from multiple references as mentioned above. I draw all the pictures myself. But if I have inadvertently infringed on any copyright, that is completely unintentional. I only make these videos to impart education. If I have accidentally violated copyright in any way, do let me know so I can make the necessary changes or give credit to anyone who is owed the same.
These videos are NOT intended for patient education. They are NOT a substitute for diagnosis and treatment by a licensed medical professional. Always seek the advice of a qualified health care provider for any questions you may have regarding any medical condition, so that they can address your individual needs.
🔅They are ONLY meant to help students of medicine and health sciences with studying, and should be used for just that purpose and absolutely nothing else.
Byte Size Med. All Rights Reserved.
Went from sea level to 6,300 feet. Went from Running 5 miles a day to a 10 minute walk a day. It’s unbelievable what high altitude does to you.
Wow, I've watched 10+ video's on this topic but yours incorporated practically all elements and was much more comprehensible to boot! Awesome job, thank you very much!
You’re very welcome! I’m so glad you liked it😊
I was getting frustrated watching the Osmosis video on this topic, and quickly searched it on CZcams instead, and I'm so glad i found this video!! Thank you!!
Thank you so much for putting this much effort into simplifying this concept in the best possible way.
Described the concept in very precise and easy way... thank you🌸
Thank you so much, please keep making educational videos. Hope your channel grows bigger in the future 🥰
Amazingg ..u have taught the whole module wayy better than the my med school during 4 weeks❤️❤️
It was so nicely constructed and yea you make me love the subject more. I've watched several videos of your channel and you never fail to amaze me. Kudos to the amazing work. Keep it up :D
Thank you so much! 😊
Just moved from 700 feet to 7000 feet. Can’t wait for my body to adjust and feel normal again lol
Are you better yet?
I just moved from 7 feet to 8500 feet. I feel horrible
@@Alfreeod me tòo
As a respiratory therapist, this is the best explanation you could ever search on CZcams.
Can i ask you , if this case can be called as ( chronic type 1 respiratory failure ) ?
I tired searching
So perfectly concise that it's AMAZING ✨
I just saved my year
Thanks for the respiratory physiology playlist ❤️😌
You deserve more subscribers
Its very helpfull thanku so much for making medical so easy for us to understand ❤
I was able to understand SO well thank you❤️
it's amazing ma'am keep going we need your help to clear our concepts😊😄
thankyouuu, this is very helpful🤩
Thank you this helped me a lot ❤
This video saved my saveral hours
Thank you mam❤️
very helpful, thank you!
Maam never mind your voice is so soothing, keep inspiring us! 👍
Brilliantly explained ma'am
I just discovered your channel. Thank you for this! 💙
You’re welcome! I’m glad you like it😊
just wow!! thank you so much !!!
this topic in physio is usually skipped because it’s at the end of respiratory chapter lol but i think it should not be missed out because it’s still complex 😂
Physio here, you’re right
Thanks! Great help
This is so organized
Thank you. I wish my doctor would take this as seriously.
By any chance, would it be able for you to make a video about circulation of blood and regulation of it? Your video helps me very much :)👍🏻
Sure thing. I'll add it to my list of upcoming videos. I'm glad they're helping you! 😊
A sweet vedio i have ever watched thanks alot ❤️
Much appreciated, thank you! 😊
Thanks❤
could you please explain from where the CO2 came inorder to compensate respiratory alkalosis?, since the body already eliminate more amount of CO2 due to hyperpnea.
Thanks ❤
Nicely explained. Thanks a lot. 👍
You’re most welcome!
Thank you 😊 maam
Thissss is perfecttttt
Wow amazing ❤❤❤❤❤❤❤❤❤
Thanks
Too good
*Fantastic*
Amazing channel and very helpful in understanding guyton's concepts.... Thanks a lot....
Kindly considering making video on hyperbaric respiration, dysbarism and space physiology
Once again thank you
Thank you! I’ll have to brush up on some of those concepts, but I’ll be sure to add them to my list. 😊
amazing
Tq
thank you sooooooooooooooooooooooooooooooooooooooooooooooooooooooooo much
Does the H+ cross the blood brain barrier .The blood ph is normalized
Please upload some lectures on endocrinology
Very low pco2 will shifts the curve to the left, not to the right.
How do i get notes of this video
You wrote that hydrogen secretion is decreasing in the kidney. Is that correct? Because as far as I understand, shouldn't it increase in order to decrease the pH level?
You are so smart
God bless you
So at first hyperventilation occurs than Hypoventilation occurs and later Hyper?
Can you post the slides to this? or the notes?
Hello I have questions Why is DLCO can be elevated in patients who lives in high altitudes ?
The density of air at high altitude is low so rapid and easy movement of air through alveolar capillary memb and easy diffusion might be the only reason .
Goddess
Anyone after NCERT line from adaptation😮
In another word, human body will adapt the lower atmospheric pressure.
Give some concepts..........
High altitudes bring various changes in physiology of respiration and circulation as result of hypoxemic hypoxia , Our body shows physiological readjustments and compensatory mechanisms to the changes caused by hypoxia . And this mechanism of readjustments is called as Acclimatisation.
To make it simpler Acclimatisation is read under
¹changes in VENTILATION
²changes in CIRCULATION
¹Due to hypoxic conditions, there is increased rate of breathing and depth of breathing (hyper ventilation) this results in increased loss of carbon dioxide leading to RESPIRATORY ALKALOSIS (PH Lowered)
In response to this altered PH of CSF And BLOOD, firstly central chemoreceptors detect reduced H+ ions -------> Reduce hyperventilation ------->PH of csf back to normal . Secondly Kidneys Lowers H+ secretion and HC0³ reabsorption -----> PH of blood back to normal .
² changes in CIRCULATION :
Hypoxia is potent stimulus for Renal erythropoetin production .
Hypoxia ----> stimulates erythropoetin gene-----> Production of more RBC -----> POYCYTHEMIA .
POYCYTHEMIA on one hand helps to cope up with the hypoxic conditions on the other hand causes increase in viscosity of blood and inturn increase in resistance of blood flow ------>low perfusion of blood in tissues .
Increased RBC -----> increased 2,3 DPG ------>reduces affinity of Hb towards O2 .
Hypoxia on
systemic vessels ------> vasodilation
Pulmonary vessels-------> vasoconstriction
Due to increased capillary pressure causes Pulmonary edema and cerebral edema.
All this i grabbed from this video itself .
Hope u find it helpful too . ✌
@@Muskaan__12345 thank you
Thanks its too good and very.much comprehensive...upload more topics and video and plz keep going
From 760mmHg to 87? Are you Kidding?