Granulation - In process checks in Pharmaceutical industry l LOD l Interview Question and answers

Granulation - In process checks in Pharmaceutical industry l LOD l Moisture content l Interview Question and answers
-----------------------------------------------------------------------------------------------
Pick your favourite topic video from below playlist:
1. QMS - Quality Management System in Pharmaceutical industry : • QMS - Quality Manageme...
2. QA- Quality assurance in Pharmaceutical industry. : • QA- Quality assurance ...
3. QC - Quality Control in Pharmaceutical industry :
• QC - Quality Control i...
4. OSD - Tablet Manufacturing in Pharmaceutical industry :
• OSD - Tablet Manufactu...
5. Injectable processing - Injectable processing or Sterile dosage formulation : • Injectable processing ...
-----------------------------------------------------------------------------------------------
Questions covered:
Q. What are the important in-process checks performed during granulation process ?
Q: Which USP chapters are referred for Granulation in-process checks ?
Q. What should be the frequency for in-process checks done during granulation process ?
Q. How is Loss on Drying measured in the granulation process ?
Q. What is formula to calculate % Loss on drying ?
Q. How loss on drying can be adjusted during granulation process?
Q. What is the acceptable moisture range in granulation processes, and how is it determined??
Q. Why is controlling moisture crucial / important in granulation ?
Q. What is the typical range of Bulk Density values in granulation, and how does it vary with different formulations ?
Q. Can variations in Bulk Density affect the compressibility of granules during tableting ?
Q. How is Tap Density measured, and what equipment is commonly used in granulation processes ?
Q. What factors can lead to fluctuations in Bulk Density during the granulation process ?
Q. During tap density measurement what is fixed drop height and dropping speed?
Q. How is the Granulation Endpoint typically determined during granulation process ?
Q. Why is it important to avoid over-granulation in the granulation process ?
Q. How does the appearance of granules change as the Granulation Endpoint is approached?
Q. How is Particle Size Distribution typically measured during granulation ?
Q. What impact does particle size distribution have on the compressibility of granules during tablet manufacturing ?
Q. How does the particle size distribution influence the dissolution profile of tablets in pharmaceutical formulations ?
Q. How is Granule Flowability typically evaluated during granulation ?
Q. What is formula for Carr Index and Hausner Ratio?
Q. What factors can influence the flowability of granules in the granulation process ?
Q. How does poor granule flowability impact the efficiency of tablet manufacturing ?
Q. What are the key aspects to be observed during Visual Inspection of granules ?
Q. How is Dissolution Testing typically conducted for granulated materials ?
Q. What factors can influence the results of Dissolution Testing for granulated materials ?
Q. Describe the importance of blend uniformity in tablet manufacturing ?
Q. Why is dissolution testing important during the granulation process ?
Q. What procedures are used for Binder content verification and pH measurement of granulation mix ?
Q. Why in process checks or testing is important in granulation process ?
-----------------------------------------------------------------------------------------------
Keywords to find this video:
granulation process in pharmaceutical industry,pharmaceutical industry,process validation in pharmaceutical industry,pharma production interview questions and answers,sterilization processes in the pharmaceutical industry,pharma interview question and answers,production interview questions and answers,pharma production interview questions and answers.,pharma interview questions and answers,pharma job interview questions and answers
-----------------------------------------------------------------------------------------------
Copyright disclaimer:
“Any illegal reproduction of this content will result in immediate legal action.”