Childhood Trauma & Multiple Sclerosis: A Study Overview
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- čas přidán 1. 08. 2024
- In this video, our co-founder, Brett Drummond, summarises a recently published study by University of Illinois at Urbana-Champaign researchers, where they used an animal model to investigate how early life trauma may impact on multiple sclerosis.
The open access paper referenced in the video is available here:
www.nature.com/articles/s4146...
If you have questions on any aspects of this video, please comment below or email them directly to Brett at brett@mstranslate.com.au.
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Dr. Gabor mate has already explored and studied this concept. Read his book entitled..when the body says no..exploring the stress disease connection. Chapter 2 is about MS.
Thank you
btw. My whole life has been one trauma after another. I think my MS is something like PTSD.
Had a traumatic head injury when i was 5, followed by 12 additional concusions up to the age of 18. Diagnosed with MS at 31.
Same here
Thanks for presenting another interesting study, Brett! I found this one quite interesting for two reasons. Firstly, I would never have thought this could impact the immunesystem. Secondly, I did actually suffer some (relatively) significant trauma in early-life myself. My parents separated when i was three, and less than a year after i suffered an incident with a boiler that left me with roughly 15% of my body covered in third-degree burns. Several surgeries ensued. I also had quite an aggressive onset of disease radiologically three years ago, with around 30-40 brain lesions and two C-spine lesions.
Hi Markus, thanks for the kind words and for sharing such personal experiences with us. I also think it is an interesting area, especially seeing as this is now identifying actual physiological changes that seem to occur (in the mouse study anyway) as a response to this sort of early life trauma. It will be interesting to see how this area of research continues to develop and we will make sure that keep providing updates whenever they are able. Thanks again - Brett
Thank you for making these studies more comprehensible
Hi, this is very interesting. I suffered childhood trauma due to a drowning incident when I was nearly 5. I was diagnosed with MS 2 years ago at the age of 54. My neurologist and I have traced back to when I first started to show symptoms. This happened at about the age of 27. It just took a bad relapse to add all symptoms together and an MRI to diagnose. I had a severe relapse 18 months later, spent 6 weeks in hospital and have now progressed to SPMS. Will be interesting to see what comes out of this research.
Hi Lucinda, thank you for sharing your experiences with us. It certainly is interesting research and we will make sure that we provide updates as soon as they are published. Considering your story, you may also be interested in an interview that I did late last year with Professor Helen Tremlett, where she discusses the MS prodrome. You can watch that video at the link below, please let me know your thoughts, I'd love to hear how you think it lines up with your personal experience: czcams.com/video/kgH7-MS-av8/video.html . Thanks again - Brett
Petr Shamraev is treating multiple sclerosis with psychotherapy via Skype. He has good results.
I suffered childhood trauma, started age 4 with a friend who tried to kiss me, at 5 I was shut in a basement by my neighbors, at 6 my mom pulled my hair twice, at 7 she was in a car accident left a TBI, other than that my parents bought me their love rather than showing it..on my occasions. I had to go to wakes all open casket, parents took me to Court in 2001 at 21, mom just wanted to be my guardian. I semidated a controlling, jealous, girlfriend who was argument starter, a blamer, she was bipolar and a Jehovah Witness.. 3 years of it, so not surprised how I wound up with MS.
I was diagnosed at 28 (13 years ago)
This is interesting but isn’t a limitation that these mice are already genetically primed to develop MS? As in, it’s interesting that trauma may speed up the onset and severity of symptoms in susceptible people but what’s the practical application of that? Looking at this quite critically, in humans the biggest difference in MS symptoms is between people who do or do not develop MS. Surely studying the difference between these two groups is more likely to result in findings that can usefully be applied to treatment and outcomes for MS sufferers. At this point we know trauma basically increases the risk of all chronic health diseases and yet there have been very few well evidenced advances in treatments for people affected by trauma. Psychiatry has barely changed in the last century.
Mind you, the knowledge regarding the adaptations in the immune responses is interesting and perhaps that will lead to worthwhile advances.
Interesting information. Specific examples of trauma would be helpful. Physical, psychological, mediction SE or disease etc..
I have MS and I first thought that this doesn't affect me. Then I remember that I had three things. First I was born premature, then was attacked by a dog when I was about 2 and when I was 9, I lit the upstairs of my house on fire. On the other hand, I am a US Air Force veteran. I read that Vets have higher rates of MS than the general population. Enough so that the VA grants compensation if symptoms appear within 7 years of service.
Hi Einarr, thanks for your comment. It is always difficult with research like this to think back and wonder how might it have applied to a personal situation. This data comes from very early research, so we will have to see how it progresses, but it ties in with other work that has suggested that stress could play a role. I do know that there is a large database of information on the rates of MS from the VA, as they do a lot of research in the area, I will look to see what some of their latest publications are and aim to provide a summary in the future. Thanks again for your interest - Brett
I was diagnosed with MS when I was 15. Diagnosed with PTSD when I was 18 and I was recently diagnosed with C-PTSD at age 25. My childhood was traumatic because of my mother who had untreated BPD until I was 14.
Could that have had a factor in me getting MS?
Hi Cheryl - thank you for the comment and question and apologies for the delay in responding. Unfortunately, at this stage we don't know how findings like this transfer across to people living with multiple sclerosis, so it isn't possible to provide an answer to that question. There has been a recent interesting study that has looked at how PTSD impacts people living with multiple sclerosis. I will do a video on that in the near future. If you subscribe to our channel, you should get a notification when it becomes available. Thanks - Brett
@@MStranslate1 can you share a link to your video on PTSD and MS? Very interested. Thx!
Im not a professional but I personally believe that having a personality disordered parent, especially a mother contributes to autoimmune disorders like MS. Mothers create the framework of our nervous system.
Interesting, the CDC in the US looked at early on and porolonged childhood abuse and concluded that the likelihood to develop an autoimmune disease during lifetime is over 50%. New research also shows that the microbiome being unhealthy us a connection. However, stress as in high cortisol levels and adrenaline effect the microbiome. So that is where a possible connection is?! And my question is, how much do hormones play a role in progression of disease. A lack of Estrogen or pregnancy seems to change it.
Thank for giving access to those very interesting studys and for explaining the outcomes so precice and short and bringing it to the point..
Thank you very much for the kind words Thea. I'm glad that you liked the video and found it interesting, informative and easy to understand. It's my pleasure and I look forward to bringing you more new content in the near future. Kind regards, Brett
Around age 8 or 7 I fallen from stairs 3 times where I hit my head and neck, didn't go to hospital then at age 9 or 10 left my country peru to go to usa left my mom in peru and went with my father, I thought I had adhd but i think it affected me sexually and cognitively and it would explain my eccentric behavior in my whole life but hasn't taken my intelligence.
away for people with tbi we can still be strong and learn to breath correctly and have conscious of our body, now at 24 I'm thankful that I know that I wasn't a bad kid or couldn't focus in school or adapt at my environment, I had neck problems in my childhood growing up, this explains my eccentric behavior.
What types of childhood trauma would be applicable? Only separation from the mother? Thank you for all your work.
Hi Suzanne, thanks for the great question. It's probably one that we need a better understanding of at the moment, especially in terms of human studies. In this study, they used a combination of both the emotional stress (separation from the mother) and physical trauma (injection) and found that the most meaningful changes were seen when only both were applied (they also tested each one individually). In the human studies that I mentioned, this was mostly due to emotional/psychological trauma. In saying that, other studies have seen that physical trauma, such as a concussion, can have an impact on the development of MS later in life. Hope this answers your question and thanks again for your engagement with this video - Brett
@@MStranslate1 Thanks so much for you reply Brett 😊
@@MStranslate1 You need a further study? Why, because it's set perfectly, chronic stress lowers the immune system, the body may go into shock and BAM just diagnosed, and there's other articles back up this.
Been scapegoated, emotionally, sexually and physically abused in different parts of my childhood so
I was wondering if my MS had any explanation besides "doctors dont known"
As far as I know, childhood trauma (high levels of stress) increases the risk of autoimmune disorders in adulthood, any kind of autoimmune disorder.
Regarding MS, the only thing that is fairly clear is that MS patients had mononucleosis around 10 years before the start of the MS symptoms.
See lots of people in the comments talking about their childhood trauma and autoimmune disorders..however, most people aren't aware that they've been traumatized, neglected, even abused. Really, most people do not have the awareness of their own childhoods, sadly. Because, potentially, people who change their core beliefs, often improve their symptom's.
Been diagnosed with rrms last year at the age of 26. Before that I been having numb legs for the past 4 years, it started with my left leg and it lasted for a month or two, then it switched to right and left again. I kept going to the general practitioner for that but they only tested my blood till my left arm went numb, then they sent me to a neurologist ... such a shitty general practitioner bc now i have trouble walking and can barely walk 1 kilometers, that coul’vr been avoided. I have medicine but yea.. its not getting any better of course.
And i didnt know anything about ms so i did research about what else can get effected and how why etc. And looking back i been having blurred vision (together with a weird headache / light headed feeling) from time to time and that goes back for like 10 years and i also went to the doctor for that but they never came to a conclusion... the dutch.. so called good health care kinda fucked me over...
But yea the only thing i could think of why i have this so early in life is childhood trauma.
And that leading to hating life and myself.
Itachi Uchiha * I can understand why your sad and upset with your life!! Your Dr for whatever reasons, missed your symptoms! This gave MS the opportunity to wreak havoc on your body! Trust me, I know the frustrations your experiencing, only too well. Dealing with an unknown illness is bad enough. But to realize your own Dr through his incompetence, allowed your MS to advance unchecked 😳.
I'm normally a happy person, I love making others laugh, I love to encourage people, lift them up when their low.
But I became a different person after my diagnosis, for the above reasons. The depression started consuming me. I became withdrawn from my loving family. It was terrible. I'm only speaking about myself here......... I became so tired of being miserable and I totally disliked who I was becoming. I've always believed in God our creator, Jesus Christ. One day I laid flat out on my floor and begged for God to forgive me, and change the miserable person I was becoming. I renewed my faith and belief in Him. I accepted His death on the cross as the punishment for my sins, because I'm a sinner, just like every other human being on earth. Jesus died on the cross for our sins, was buried, rose from the dead on the third day, and ascended into heaven. He now sits at the right hand of God the Father, until the day He comes back to gather His children, the ones who truly believe in and follow Him. After my sincere prayer, I felt immediate relief. Like a dark cloud was lifted off me 😁. Our loving God forgave me❤️ and took all my burdens away, for He cares for me. His peace, unconditional love and strength have breathed a desire for life back into my soul, regardless of MS!! 😁 God's message to His children today, is don't give up! God is much closer than you realize, He is only a prayer away 🤗❤️ God Bless All
I hear you ❤
I was diagnosed with MS when I was 14. I would say that I suffered some traumatic instances during my childhood, especially since my younger sister was diagnosed with a heart condition when she was born. In addition to that, I can recall how my mom's younger sister that was visiting from China ended up passing away after having what we believe to be west nile virus. if anything, I'm 27 now and got a divorce from mr MS 3 years ago (I was kicked out of their house due to troubles with standing up for myself/teen angst/sexual and was able to escape a homicidal traumas) because of all of the domestic violence from the ex husband that decided to isolate me. once I ran back to my parents, I survived a string of attacks where I had optic neuritis every other month to the point where I went completely blind....I'm wondering if there would be any way that I might be able to contribute to this study
Thank you for sharing such personal experiences with us Josephine and I'm sorry that you had to endure such hardship and trauma throughout your life. At this stage, I'm unsure as to whether these researchers are progressing to any human studies. We will keep an eye out for any other trials on this topic and provide updates once they are available. If you subscribe to our channel, you should receive a notification any time we publish a new video. Thanks - Brett
I was born into a happy family beeing an only child for the first five years. Then everything changed because of the birth of my brother who was born sickly: ear infections from three das old, he was screaming his lungs out day and night and got all of my parents time and care. I really hated him for stealing my parents… I had to start fending for my self ang got in to self abuse very early, had an outgoing sexual behaviour at the time of seven, got in to all kind of trouble in my teens until I left home and moved 300 km away from my “family”. Now at 56 I have had ms since probably 25 years but got the diagnoses -14. Before that I had endometriosis (and a lot of other auto-immune deceases) for years and years, trouble connecting the connect way with people especially loved ones- I’d rather leave them before they left me. Then i was lucky enough to find a true loving husband about 30 years ago but at times I still find the little miss understood girl in my heart… I can still easily turn into self harm however much milder and I’m tend to be boundless with new relations still even though I’ve worked among other things as a headmistress focusing on neglected children. Today I’m much stronger much thanks to my husband’s deep love and care! Today I’m self employed working with bosses- we all need someone willing to listen!❤️
Do these mice have EBV antibodies?
Parents were expats so when I was younger I moved around every 4 years - ripped from any social group and forced to leave friends behind until age 12 ish - then when I was 18 moved to a completely different country for my BSc studies. My entire life / friendships have been built on quicksand and caused some emotional pain for sure. My parents also argued a lot when I was a child (weekly shouting matches that made me incredibly stressed to the point I would cry). My father also caused me a lot of emotional stress - he made me feel like I was worthless. From 15-18 I was also relatively depressed although never diagnosed or had meds for it. Now at 27 I have been diagnosed with MS. I do wonder if there is a connection :/
you can try using homeopathic medicine plumbum met dilution to treat multiple sclerosis.
100 right 👌
What could someone do to offset the effects of the early childhood trauma? I think that would be the first question that needs to be answered.
Hi Katherine, thanks for the question. At the moment, that is probably something that is still unclear, however, this study has shed some potential light on this. The study did identify a pathway that seems to be important in the outcomes seen in the mice that experienced early life trauma. Having identified this, they then looked at ways that they could target this pathway for potential therapeutic benefit. The results from that were quite positive. This suggests that if a similar observation is found in people living with MS who have experienced early life trauma, it may open new avenues for treatment specifically for these individuals. Thanks again for a great question - Brett
Ask Jesus to answer your question He is the way the truth and the life. I promise you He will answer you 🙏
I like the diet and overcomingms.org although there are others. Also, consider seeing a naturopathic doctor as they cure diseases and replacing the medical doctors.
@@margaretmansfield6372 i have tried the jesus bs, never worked!
I would say inner healing, self care, and reducing the stress in our lives will be very helpful.
Stress
It's not ok to test on animals
No excuse for abusing animals in this kind of research. The researchers could easily have carried out a study on humans using historical data instead
It's not informative.
Yes..this is garbage science..why write about this and not EBV.
@@barbaradascalos4411 Agreed Barb. Í had lot of traumatic events, like maybe some of us.. but he could've also touched on EBV.
What about stress in adulthood. Why just childhood trauma. I agree there is a big connection between EBV and low vitamin D in MS.
What about people who lived through the holocaust..did they all get ms..? NO!
@@barbaradascalos4411 You don't if survivors didn't, few míght have. Why be quick to dismiss something?