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Lipid‐Based Nano‐Delivery for Oral Administration of Poorly Water Soluble Drugs (PWSDs): Design, Optimization and in vitro Assessment Go through this paper, I found it helpful for the topic

Create ternary plot diagram. Depending upon the excipients of your desired formulation ternary plot will be pseudo, or ternary plot. Pseudo: where oil, water, surfactant and co-surfactant mixture create an isotropic formula. Normal ternary plot: co-surfactant will be absent. 3 components will be create an isotropic formula. Ternary create by water titration and their data obtained from that titration. If the information is helpful. Please subscribe the channel do like and share.

microemulsion should be clear and transparent but im getting turbidity after titration with water just like emulsion. Any solution for this

Is it turbid, after incorporating in the delivery media? Check it. If it is not. Then it's ok If it is, then please develop your formula by altering excipients

Dissolve the emulsion in a oil soluble or water soluble colour and observe under digital microscope.

Thanks Pratik, for asking the question. First of all you do not get the emulsion if you not add the water into the system. Secondly, the actual formulation doesn't contain any water. It will only contain surfactant, co-surfactant, and oil. This three components will incorporate into a capsule. After reaching the capsule into the target site, with your swallowed water approx 200 ml will emulsify and produce the SMEDDS. Which further penitrate into our body. If the answer is not satisfactory please tell to describe more, where you don't reach in this topic. If it is helpful please subscribe my channel dear. Thank you

Welcome dear

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Thank you so much 🙂

Thanks

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