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Working Session - Accelerate Study and Natural History Study
Moderator Grant Schulert & Alexei Grom
Participants: Scott Canna, Ed Behrens, Tiphanie.Vogel, Bryce Binstadt, Lauren Henderson, Mona Riskalla, Beth Gottlieb, Randy Cron, Bas Vastert, Claudia Bracaglia
zhlédnutí: 65

Video

Final Working Session
zhlédnutí 21Před 2 lety
Final Working Session
SJIA Lung Disease Cytokine Plasticity Hypothesis - Peter Nigrovic & Bruce Binstadt
zhlédnutí 201Před 2 lety
SJIA Lung Disease Cytokine Plasticity Hypothesis - Peter Nigrovic & Bruce Binstadt
Searching for Historical Control for Refractory SJIA Trials
zhlédnutí 41Před 2 lety
Contents: Panel moderated by Grant Schulert 0:00 - Searching for historical controls in existing datasets: Bas Vastert 13:50 - Questions /Comments 27:30 - CARRA Registry Systemic JIA Data: Yuki Kimura 42:43 - Questions /Comments 49:30 - CARRA SJIA-LD Cohort Study - February 2022 update: Grant Schulert 57:50 - Questions /Comments
Patient Perspective for Lung Disease in SJIA
zhlédnutí 77Před 2 lety
Contents: 0:00 - Patients stories 7:05 - IL-18 Inhibitor (MAS825) Patient Experience 11:49 - Different medications patients are on and patients comments 20:03 - Questions / General comments
Summary of Challenges in Refractory SJIA Trials - Rashmi Sinha
zhlédnutí 33Před 2 lety
Summary of Challenges in Refractory SJIA Trials - Rashmi Sinha
Lung Ultrasound to track lung disease in SJIA LD Patients - Patricia Vega
zhlédnutí 126Před 2 lety
Lung Ultrasound to track lung disease in SJIA LD Patients - Patricia Vega
The Role of External Controls in FDA Decision Making - Veronica Miller
zhlédnutí 37Před 2 lety
The Role of External Controls in FDA Decision Making - Veronica Miller
Retrospective Natural History Study in SJIA & MAS
zhlédnutí 42Před 2 lety
Contents: 00:00 - Natural History Studies as a source of external controls in refractory SJIA trials: Fabrizio DeBenedetti 3:33 - Discussion Invited Comments from FDA (Kerry Jo Lee, Nikolay Nikolov) 18:00 - Proposal for retrospective chart review as an external control group: Alexei Grom & Fabrizio DeBenedetti 22:50 - Discussion Invited Comments from FDA (Kerry Jo Lee, Nikolay Nikolov)
How to include refractory SJIA w/out arthritis in Clinical Trials?
zhlédnutí 69Před 2 lety
Contents: 0:00 - Patient Perspective on Refractory SJIA w/out Arthritis Patient Panel: Zulayka Martinez, Anna Carlson, Cappy Culicchia, Leah Bush 15:12 - Proposals for including Refractory SJIA w/out Arthritis in Clinical trials Moderator: Hermine Brunner Proposals for including this patient group: Fabrizio DeBenedetti 23:15 - Panel Discussion Invited Comments from FDA (Nikolay Nikolov)
How to overcome barriers to MAS Clinical Trials?
zhlédnutí 84Před 2 lety
Contents: 00:00 - Patient Perspective on MAS & Clinical Trials: Patient Panel - Regina Minerva, Sarah Tronsdal, Robyn Rivera 23:03 - Barriers to MAS Trials: Alexei Grom & Fabrizio DeBenedetti 35:00 - Panel Discussion Invited Comments from FDA (Nikolay Nikolov)
It is Time for IL18 Driven Clinical Trials
zhlédnutí 239Před 2 lety
Contents: Panel moderated by Dan Lovell: 0:00 - Fabrizio De Benedetti & Scott Canna : It is time for IL-18 driven clinical trials in autoinflammatory disease 23:00 - Ed Behrens: Case study of patient with IL18 inhibitor usage in SJIA-LD 36:50 - Chris Leptak: Regulatory Perspective about Biomarkers in Drug Development
Real World Evidence for Rare Disease Clinical Trials - Isaac Kohane
zhlédnutí 67Před 2 lety
Real World Evidence for Rare Disease Clinical Trials - Isaac Kohane
The Elephant in the Room SJIA Diagnostic/Classification Criteria
zhlédnutí 67Před 2 lety
Contents: 0:00 - Panel moderated by Peter Nigrovic Panelists: Yuki Kimura, Bas Vastert, Fabrizio De Benedetti & Dan Lovell 24:00 - Discussion Invited Comments from FDA (Nikolay Nikolov)
Unmet Needs and Patients Stories
zhlédnutí 100Před 2 lety
Contents: 0:00 - Welcome & Unmet Needs in Refractory SJIA & MAS - SJIA Foundation Perspective: Rashmi Sinha 11:50 - Patient Stories Patients: Kari Cupp, Laura Bogg, Robyn Rivera, Ronny Bachrach
Working Session - SJIA Diagnostic Criteria and IL18 Trials
zhlédnutí 64Před 2 lety
Working Session - SJIA Diagnostic Criteria and IL18 Trials
Distinct Clinical Phenotypes in Refractory SJIA & MAS - Alexei Grom
zhlédnutí 123Před 2 lety
Distinct Clinical Phenotypes in Refractory SJIA & MAS - Alexei Grom
BMT in Refractory SJIA-Lung Disease
zhlédnutí 448Před 2 lety
BMT in Refractory SJIA-Lung Disease
A Lifetime with SJIA - Nicole Dalton
zhlédnutí 243Před 2 lety
A Lifetime with SJIA - Nicole Dalton
The Many Faces of Refractory SJIA - Parent Panel
zhlédnutí 109Před 2 lety
The Many Faces of Refractory SJIA - Parent Panel
MAS: Old and New Treatments - Scott Canna
zhlédnutí 89Před 2 lety
MAS: Old and New Treatments - Scott Canna
What is Stills Disease and Strategies for Treatment - Petros Efthimiou
zhlédnutí 333Před 2 lety
What is Stills Disease and Strategies for Treatment - Petros Efthimiou
What is SJIA and Strategies for Treatment: Alexei Grom
zhlédnutí 219Před 2 lety
What is SJIA and Strategies for Treatment: Alexei Grom
Some Interesting SJIA-LD Cases from around the world
zhlédnutí 28Před 2 lety
Some Interesting SJIA-LD Cases from around the world
SJIA-LD Research Updates: Vivan Saper
zhlédnutí 22Před 2 lety
SJIA-LD Research Updates: Vivan Saper
SJIA-LD Research Updates: Grant Schulert
zhlédnutí 16Před 2 lety
SJIA-LD Research Updates: Grant Schulert
SJIA LD Research Update - Adriana Almeida De Jesus
zhlédnutí 30Před 2 lety
SJIA LD Research Update - Adriana Almeida De Jesus
SJIA-LD Research Updates: Scott Canna
zhlédnutí 16Před 2 lety
SJIA-LD Research Updates: Scott Canna
Global Perspecitves on Treating SJIA
zhlédnutí 40Před 2 lety
Global Perspecitves on Treating SJIA
Bridging the Gap Between SJIA and Still's
zhlédnutí 32Před 2 lety
Bridging the Gap Between SJIA and Still's