Molecular Imaging & Therapy
Molecular Imaging & Therapy
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Video

Why are dose constraints from EBRT not directly transferable to radiopharmaceutical therapy (RPT)?
zhlédnutí 559Před měsícem
Invited Speaker Dr. Tahir Yusufaly (April 23, 2024); Faculty Member at Johns Hopkins University Department of Radiology. Chapter breakdowns: 0:00 Introduction 1:30 Dose distribution in RPT vs. External Beam Radiotherapy (EBRT) 8:42 Brief overview of EBRT radiobiology 27:06 Efforts towards a more universal Biologically Effective Dose (BED) 39:24 Efforts towards a more universal normal tissue com...
We're (not) fine: Lack of fairness in AI-based medical image diagnostic tools (Dr. Seyyed-Kalantari)
zhlédnutí 332Před 3 měsíci
Invited Speaker Dr. Laleh Seyyed-Kalantari (Feb 22, 2024) Dr. Laleh Seyyed-Kalantari is Assistant Professor of Electrical Engineering and Computer Science, at Lassonde School of Engineering, York University. Before that, she was an Associate Scientist at Lunenfeld Tanenbaum Research Institute, Toronto, Canada. With a Ph.D. in electrical engineering from McMaster University (2017), she was an NS...
Noise-Bias & Contrast-Noise Analysis in Medical Imaging
zhlédnutí 490Před 4 měsíci
What's Noise in imaging? What's Bias? What's Mean Squared Error (MSE), and how does it relate to noise and bias? What are Noise vs. Bias Trade-off Curves? What's Contrast? What's Contrast-to-Noise Ratio (CNR)? What's the Rose criterion? What's the Contrast Recovery Coefficient (CRC)? How do these metrics relate to each other and different image reconstruction & generation methods? 0:00 Introduc...
Predictive Oncology Through Image-Based Mathematical Modeling (with Dr. Tom Yankeelov)
zhlédnutí 561Před 8 měsíci
Predictive Oncology Through Image-Based Mathematical Modeling
A Guide to Cross-Validation for AI (with Dr. Tyler Bradshaw)
zhlédnutí 394Před 8 měsíci
Chapter breakdowns: 0:00 Introduction 3:09 Overfitting vs. generalizability 6:24 Pitfalls of using one-time split method 6:44 Pitfall #1: Non-representative test set 11:24 Pitfall #2: Tuning to the test set 19:12 Cross-validation 20:10 Important note: in CV we are testing pipeline, not a single model 22:25 K-fold, folded test set 27:30 K-fold, hold-out test-set 32:56 Nested cross-validation 41:...
Apples or Kiwis? Is 23Gy kidney absorbed-dose limit the way to go for radiopharmaceutical therapies?
zhlédnutí 635Před 11 měsíci
Clinical trials for radiopharmaceutical therapies (RPTs) are usually limited to 23 Gray absorbed dose to kidneys. However, this value seems arbitrary when considering its source: a publication for external radiation beam therapy (EBRT) dating back to 1991, itself referring to a paper in 1968. The existing limit in fact neglects inherent differences between RPT and EBRT. In this episode, Nuclear...
Why Take & How to Prepare for the American Board of Science in Nuclear Medicine (ABSNM) Exam
zhlédnutí 865Před rokem
Dec 27, 2022; In this video I share information, thoughts, experiences and recommendation for taking the ABSNM board exam Additional content referred to in the video: Our Nuclear Medicine Physics Lecture Series Playlist: czcams.com/play/PL0FpKQ-EgTObAsB7r1bGbdBdOkt5f1W-z.html Condensed Nuclear Medicine Physics Review talk (4.5 hours): czcams.com/video/HEWno48iV_U/video.html Book Erratum/Correct...
Total-Body PET Kinetic Modeling and Its Applications (with Dr. Guobao Wang)
zhlédnutí 1KPřed rokem
What is total-body PET? Why do kinetic modeling? What can they do together? Exciting applications and new horizons.
Towards Digital Twins for Precision Medicine
zhlédnutí 601Před rokem
Digital Twins for Virtual Clinical Trials towards Personalized Healthcare Delivery. Theranostic Digital Twins. Use of Artificial Intelligence. Storage/Sharing/Anonymization. The Future is Bright! Keynote Speech at the 3rd International Workshop on Multiscale Multimodal Medical Imaging (MMMI) at MICCAI 2022 Conference, Dr. Arman Rahmim; Sept 22, 2022 See also: "A Brief History of Digital Phantom...
Nuclear Medicine Physics: A Review
zhlédnutí 7KPřed rokem
4.5 hours of Essential Nuclear Medicine (see chapter breakdowns below). Target Audience: Residents, Fellows, Undergraduate & Graduate Students, Technologists 0:00 Introduction 3:15 What is Nuclear Medicine? 21:13 Nuclear Medicine Imaging 25:23 Gamma Camera 47:39 Energy Spectra in Scintillation Detectors 1:03:07 Collimators 1:27:51 Quality Assurance 1:44:00 Introduction to Tomography 1:52:53 Ima...
Dosimetry-Based Radiopharmaceutical Therapy (With Dr. Jean-Matheiu Beauregard) - why and how
zhlédnutí 1KPřed rokem
Dosimetry-Based Radiopharmaceutical Therapy is important, and can be done. Moving beyond empiric, one-size-fits-all therapies. Understanding uncertainty and variability in absorbed doses without/with dosimetry. Dose-response relationships. Single-time-point dosimetry.
Multitracer PET Imaging (With Dr. Dan Kadrmas) - Why and How + Applications
zhlédnutí 885Před rokem
Why and how to do multitracer PET imaging! Overview of techniques and considerations, and exciting upcoming applications. With Dr. Dan Kadrmas: dan.kadrmas@mfimage.com
Myth or Fact? We Cannot Perform Routine Dosimetry For Radiopharmaceutical Therapies
zhlédnutí 1,1KPřed 2 lety
Radiopharmaceutical therapies have shown great promise to treat different disease such as prostate cancer and neuroendocrine tumors. Currently, however, they follow a population based approach in which every patient is treated the same. Can we move into personalizing radiopharmaceutical therapies? That would involve performing routine internal dosimetry. In this episode, Nuclear Jimmy and invit...
Theranostics: the future for prostate cancer treatment is here!!
zhlédnutí 1,9KPřed 2 lety
Nadine Colpo RTNM and Caroline Williams RTNM, nuclear medicine technologists at BC Cancer Vancouver, present to us the exciting world of theranostics for prostate cancer. Watch as they guide us through the history (past, current, and future) of radiopharmaceuticals that target the prostate specific membrane antigen (PSMA). You will learn how the theranostic approach for treatment of metastatic ...
Simulation Software To Better Understand Nuc Med Imaging [L42] - Invited Speaker Dr. Barry Pointon
zhlédnutí 706Před 2 lety
Simulation Software To Better Understand Nuc Med Imaging [L42] - Invited Speaker Dr. Barry Pointon
Task Based Image Quality Assessment (Part 1) [L43] - Invited Speaker Dr. Abhinav Jha
zhlédnutí 788Před 2 lety
Task Based Image Quality Assessment (Part 1) [L43] - Invited Speaker Dr. Abhinav Jha
Task Based Image Quality Assessment (Part 2) [L44] - Invited Speaker Dr. Abhinav Jha
zhlédnutí 441Před 2 lety
Task Based Image Quality Assessment (Part 2) [L44] - Invited Speaker Dr. Abhinav Jha
Internal Dosimetry: Quantitative Imaging (Part 1) [L45]
zhlédnutí 877Před 2 lety
Internal Dosimetry: Quantitative Imaging (Part 1) [L45]
Quality Assurance/Control in Nuclear Medicine [L41] - Invited Speaker Dr. Barry Pointon
zhlédnutí 2KPřed 2 lety
Quality Assurance/Control in Nuclear Medicine [L41] - Invited Speaker Dr. Barry Pointon
Internal Dosimetry: S-Values & Dose Estimation Techniques (Part 5) [L49]
zhlédnutí 1,9KPřed 2 lety
Internal Dosimetry: S-Values & Dose Estimation Techniques (Part 5) [L49]
Internal Dosimetry: Radiopharmaceutical Therapies (Part 4) [L48]
zhlédnutí 607Před 2 lety
Internal Dosimetry: Radiopharmaceutical Therapies (Part 4) [L48]
Internal Dosimetry: Dose & Biological Considerations (Part 3) [L47]
zhlédnutí 546Před 2 lety
Internal Dosimetry: Dose & Biological Considerations (Part 3) [L47]
Internal Dosimetry: Quantitative Imaging (Iterative Image Reconstruction) (Part 2) [L46]
zhlédnutí 680Před 2 lety
Internal Dosimetry: Quantitative Imaging (Iterative Image Reconstruction) (Part 2) [L46]
Introduction to Kinetic Modeling (Part 2) [L40]
zhlédnutí 1,5KPřed 2 lety
Introduction to Kinetic Modeling (Part 2) [L40]
Introduction To Kinetic Modeling (Part 1) [L39]
zhlédnutí 2,8KPřed 2 lety
Introduction To Kinetic Modeling (Part 1) [L39]
What is the Standard Uptake Value (SUV) in PET and SPECT Imaging? [L38]
zhlédnutí 9KPřed 2 lety
What is the Standard Uptake Value (SUV) in PET and SPECT Imaging? [L38]
PET Imaging: More Data Corrections (Part 5) [L37]
zhlédnutí 1,4KPřed 2 lety
PET Imaging: More Data Corrections (Part 5) [L37]
PET Imaging: Data Corrections (Part 4) [L36]
zhlédnutí 4KPřed 2 lety
PET Imaging: Data Corrections (Part 4) [L36]
PET Imaging: Important Technical Advancements (Part 3) [L35]
zhlédnutí 3,4KPřed 2 lety
PET Imaging: Important Technical Advancements (Part 3) [L35]

Komentáře

  • @deepikakumari-df2nx

    Love from india

  • @NuclearLabRat
    @NuclearLabRat Před 5 dny

    This is fascinating.

  • @055shubhamsonkar6
    @055shubhamsonkar6 Před 20 dny

    Hi , can you please share the ppts . Thanks!

  • @MsKa60
    @MsKa60 Před měsícem

    So very helpful, I’m on week three of the NMT program and already committed to watch all your videos 🎉🎉🎉!

  • @saifimansoori7225
    @saifimansoori7225 Před měsícem

    Aslamualekum Sir U r just doing a fabulous job Mashallah I am from india🇮🇳 I m becoming ur fan Armaan Sir allah bless u U make topic so easy that even a average student get it easily😊😊❤️❤️

  • @omidgharibi4354
    @omidgharibi4354 Před měsícem

    Answer to the question (19:35): The half-life for Re-188 is about 17 hours. After 10mins, more than 99% of initial activity still remains. So, we can assume the activity unchanged. Now we can easily multiply the activity by the sensitivity of collimator to obtain the total counts per second of Re-188: Total counts/sec = 10 MBq * 0.9 * 10^-4 = 900. Now we can calculate the number of 155 keV gamma rays counted per second which is 15.6% of the total counts: 900 * 15.6% = 140.4. If we continue counting for 10 mins, we will count a total of 140.4 * 10 * 60 = 84240 gamma rays with 155 keV of energy.

  • @bernardkiprotich2365
    @bernardkiprotich2365 Před měsícem

    Great presentation... Thanks 🙏

  • @eng.Mimi.123
    @eng.Mimi.123 Před měsícem

    Thank you all so much ! This has been an incredible series 😊 This helped me allot in starting to dig deeper into my project 🎉

  • @Pandya_715
    @Pandya_715 Před měsícem

    Nice video ❤...i am nuclear medicine student..very much useful ❤

  • @andgamhi
    @andgamhi Před měsícem

    Thanks,very nice

  • @diesbybote
    @diesbybote Před měsícem

    ❤very interested

  • @eddymcsandbag5932
    @eddymcsandbag5932 Před 2 měsíci

    thanks a lot

  • @malikzaheermalikzaheer136
    @malikzaheermalikzaheer136 Před 2 měsíci

    Please in urdu language 😢

  • @cleavlandmingins1861
    @cleavlandmingins1861 Před 3 měsíci

    P R O M O S M

  • @AndrewJReader
    @AndrewJReader Před 3 měsíci

    Great video Arman (and Tyler), very helpful!

  • @hammerandrake
    @hammerandrake Před 3 měsíci

    omg this is hilarious!

  • @hammerandrake
    @hammerandrake Před 3 měsíci

    Great videos! Thank you so much for your dedication!!

  • @jonathanlister5644
    @jonathanlister5644 Před 4 měsíci

    Very clear! It's been 20 years since I was taught this and it was too theory bound.

  • @sohailkohri7269
    @sohailkohri7269 Před 4 měsíci

    🙌🙌

  • @XdASeviX
    @XdASeviX Před 4 měsíci

    Just discovered your channel. I'm doing my PhD in radiopharmacology and greatly appreciate the breadth and depth of your videos. Thank you so much. Keep up the good work!

  • @sayanikak
    @sayanikak Před 4 měsíci

    please give referancs or evidences for""SUV derived from two seperate studies, is expected to differ by up to +/- 28% for 95% of obeservation.

    • @molecularimagingtherapy
      @molecularimagingtherapy Před 4 měsíci

      "Lodge, M.A., 2017. Repeatability of SUV in oncologic 18F-FDG PET. Journal of Nuclear Medicine, 58(4), pp.523-532."

  • @ashburnconnecttv7860
    @ashburnconnecttv7860 Před 5 měsíci

    The music = #Sucks

  • @youngglxck_4224
    @youngglxck_4224 Před 7 měsíci

    I dont understand what is c² can somebody pls explain?

    • @stephenber2114
      @stephenber2114 Před 6 měsíci

      from what i understand, c is the constant that represents the speed of light. so for E=mc^2, energy is equal to the mass of an object multiplied by the speed of light squared. in other words if you have a mass of something that is 1kg, then its energy is going to be 1 * the speed of light squared (alot of energy)

  • @user-pq2fn6cu1w
    @user-pq2fn6cu1w Před 7 měsíci

    Good presentation!

  • @Felix-iw3iq
    @Felix-iw3iq Před 8 měsíci

    How can you show that photoelectric effect is only possible if the electron is bound to an atom? (3:40) I’m confused😅

    • @omidgharibi4354
      @omidgharibi4354 Před měsícem

      A photon cannot give all its energy to an electron if its free. This is because of conservation of energy and momentum and the key point is that the photon wont exist anymore. Assume that the free electron is at rest before collision and the energy of the photon is less than 511 keV not to make a relativistic situation. If the photon gives all its energy to the electron, it wont exist after collision. Therefore, the total energy of the photon must be taken by the electron. => conservation of energy: Eph = 1/2 mv^2. Moreover, the momentum of the system must remain unchanged. => conservation of momentum: Eph/c = mv. By these two equations you will see that mvc = 1/2 mv^2 => v = 2c. We know that it is not possible for a particle to move faster than light. Now we understand why it is impossible to have a photoelectric effect if the electron is free. The same reason governs why in Compton scattering a photon cannot give all its energy to an electron.

  • @AndrewChicco
    @AndrewChicco Před 8 měsíci

    Thank you so much for this presentation. Are you able to suggest a good textbook on Computational Biology?

  • @Timbayar
    @Timbayar Před 8 měsíci

    hello, thank you for making this video. But I have a question about the estimation of SUVr. Is the SUVr a literally true equal to 1 in all examples even if a body mass is 1kg, 2kg, or 10kg? I don't think so and these SUVr meaning has to be different from each others.

  • @vishalnimesh3846
    @vishalnimesh3846 Před 9 měsíci

    Amazing .thanku for your efforts

  • @milanjana7335
    @milanjana7335 Před 10 měsíci

    IS DR. Abhinav Jha is INDIAN?

  • @elshaimae6621
    @elshaimae6621 Před 10 měsíci

    Thank you. I'm working on my master thesis and I needed this detailed explanation ☺

  • @sonwabo2011
    @sonwabo2011 Před 11 měsíci

    Thank you, gentleman. These lectures are excellent.

  • @badhmapriyadhanaraj2766
    @badhmapriyadhanaraj2766 Před 11 měsíci

    Thank you from the bottom of my heart!!!

  • @miladpeer-firozjaei8971

    😂😂👍

  • @alifeleparanj3688
    @alifeleparanj3688 Před rokem

    🤣

  • @LimonaMaria
    @LimonaMaria Před rokem

    😂

  • @baljitkaur1210
    @baljitkaur1210 Před rokem

    hi have questions about this may you help me please

  • @user-cw8vt3zc8t
    @user-cw8vt3zc8t Před rokem

    these girls that took these classes were geniuses - way ahead of me like 30 years

  • @user-cw8vt3zc8t
    @user-cw8vt3zc8t Před rokem

    sounds fancy

  • @mdumar4146
    @mdumar4146 Před rokem

    can we get pdf

  • @mdumar4146
    @mdumar4146 Před rokem

    Can we get pdf of these lectures

  • @mdumar4146
    @mdumar4146 Před rokem

    crisp#

  • @danielzambrano4497
    @danielzambrano4497 Před rokem

    Thank you for this informational video. I am a student at Lewis University researching on AI integration of nuclear medicine technology and I myself am a nuclear medicine technology major! Love this video quite detailing and insightful!

  • @lucaspaixao826
    @lucaspaixao826 Před rokem

    I believe that the use of Argon gas in dose calibrators is to increase the photoelectric absorption of photons. As Carlos stated, ionization chambers are not very sensitive to X-rays and gamma photons. The UV light issue in GM counters was new to me, so thanks!

  • @Raied48
    @Raied48 Před rokem

    can we have a translate !!

  • @Alan-qe2jg
    @Alan-qe2jg Před rokem

    Hi,can you explain that "ups" picture at 5:35?

  • @destinynow4168
    @destinynow4168 Před rokem

    yttrium 90 is pure beta emitter,it cant be used for imaging.Thank you for the video.

    • @arahmim11
      @arahmim11 Před 6 měsíci

      This is actually not true. There is a small positron emission (leading to PET imaging) and Bremsstrahlung radiation (leading to SPECT imaging), as we discuss in the course.

  • @asgharbeigi9718
    @asgharbeigi9718 Před rokem

    Thank you so much for this masterpiece. Just let me know how much Li should be added to a semiconductor detector to compensate the electron trap events inside it. In case we add Li, how do we know that our electric pulse is coming from radiation or LI?

  • @jainamsharma2442
    @jainamsharma2442 Před rokem

    Amazing content really appreciate this content provided as a prospective medical physics student

  • @UraniumGirl
    @UraniumGirl Před rokem

    Thank you for sharing :)

  • @rubayetalam8759
    @rubayetalam8759 Před rokem

    That's nice.