One of the best if not all ready the best .. very informative and clear.... I love the way you made it so clear.... thank you very much ❤️ please continue doing these .. such a great job
Need help finding a “Dopamine Agonist” that doesn’t have the side effects like C/L. What else is out there to stimulate Dopamine - without the mania, constipation and nightmares? Mucuna and B1 ( maybe not taking enough) don’t seem to be doing enough and the C/L causes other awful, debilitating ( nightmares, etc) side effects in my HWP.. But w/o the Dopamine Agonist, they aren’t as active and not wanting to do as much.. Anyone have experience w / Selegiline? Doing Mucuna, L-Dopa, L- Theanine and B1- but not making a dent yet. Am I not giving right iteration or dosage? Thanks in advance🙏🏽
Your explanation is so helpful to understand the actions of receptor pharmacology of these medicines. Would you help me to find more infomations about 5-ta 2A- 2C receptors distribution in Mesolimbic and VMPFC, DLPFC, and Insula-amygdala pathways ? And can you tell me the easiest source (illustrated books, videos, or your simple expiation then it w be so beautiful !!) to know more about the different pathways of every neurotransmitters/modulators and its functions in depth.
My questions were little bit confusing . Actually my question are: Can you please tell me about the pathways of mesolimbic, VMPFC, DLPFC, Insula-Amydala: 1). How are they connected? 2). What types of neurotransmitters are acting on or modulating these neuronal networks?. Which networks have5-HT2A-2C receptors as the predominant receptors in these networks.? 4). Can you recommend any illustrated books or videos of lectures that describe these networks? can you please tell me about the pathways of mesolimbic, VMPFC, DLPFC, Insula-Amydala: 1). How are they connected? 2). What types of neurotransmitters are acting on or modulating these neuronal networks?. Which networks have5-HT2A-2C receptors as the predominant receptors in these networks.? 4). Can you recommend any illustrated books or videos of lectures that describe these networks?
Myofascial Pain syndrome / myofascial trigger points are the most common source of perstient and chronic pain Myofascial trigger points are a constant source of nociceptive input from the periphery that lead to central sensitization. Myofascial trigger points are discrete PALPABLE hyper irritable nodules in a taut band of skeletal muscle that can only be diagnosed by systematic palpation of the soft tissue by an experienced examiner. Dry needling is unequivocally the most effective treatment to move this common source of nociception.
Thank you for the video, the presentation was great. However i believe you did not explain the pathophysiology well, you mentioned the type 4 H.S reaction as it relates to Psoriasis but never mentioned what could be the specific antigen in this case, you also did not explain why epidermal hyperplasia happens in the first place.
They're not sure about the antigen that triggers psoriasis vulgaris. I've seen LL-37, an antimicrobial peptide produced by keratinocytes, mentioned before as a possible trigger. Then it's the usual: DC to lymf nodes, T-cell activation although I would argue it's both Th1 and Th17, migration to the skin, inflammation. Can't remember which molecule, but probably a T-cell produced interleukin (12, 17, 21 or 22) stimulates keratinocytes to proliferate which causes hyperkeratosis which in turn causes even more LL-37 and cell components which further trigger the immune system
This is so interesting I had testing done for psychiatric medication and I am an ultra metaboliser. I never knew why opioids made me so sick until this video. Thank you for this understanding! I will even more avoid them.
Several errors in this lecture, and misnomers. I.e. bradycardia due to peripheral effects, where it’s really on vagus nerve stimulation. Moderate tolerance of the heart “muscle” when describing bradycardia
all 3 are similar. It just depends if it's morphine oral or IV, as most often used. Orally it's equal to Hydro, Oxy would be 1.5 that, cuz ur body takes it up better orally. But morphine IV is 3x as potent, so 2 to 3x more potent than Hydro or Oxy too..
Thanks for the video. Do you know of a website or podcast that specializes in taking a scientific and evidence based approach to anxiety disorders by looking at specific research papers or interviewing experts in the field? I've thoroughly scanned the internet and podcast world and can't find anything like this strangely.
I'm a pharmaceutical sciences student and have a test tomorrow wich will encompass schizo, parkinsons disease and alzheimer's disease and I Just wanted to thank you because your videos have been really helping me out in my studies. Greetings from Brazil!
Hey they give me haldo Dec and they blocked my d2 receptors now I got negative symptoms of schizophrenic when the negative symptoms going go away it been 9 months
Fuck I had cyclithimia at first and it progressed to the bipolar 2. I really do not want it to evolve bipolar 1. My hypomanic attacks are very pleasant,I feel a tad more talkative but they only make me feel good. Outside of hypomanic attacks I feel like shit let me have this once or twice a year treat at least. Well if they didnt happened at all it would be pretty good since I could use ritalin for my adhd at least.
One of the best if not all ready the best .. very informative and clear.... I love the way you made it so clear.... thank you very much ❤️ please continue doing these .. such a great job
Is it different when “Parkinson’s Plus”???
Need help finding a “Dopamine Agonist” that doesn’t have the side effects like C/L. What else is out there to stimulate Dopamine - without the mania, constipation and nightmares? Mucuna and B1 ( maybe not taking enough) don’t seem to be doing enough and the C/L causes other awful, debilitating ( nightmares, etc) side effects in my HWP.. But w/o the Dopamine Agonist, they aren’t as active and not wanting to do as much.. Anyone have experience w / Selegiline? Doing Mucuna, L-Dopa, L- Theanine and B1- but not making a dent yet. Am I not giving right iteration or dosage? Thanks in advance🙏🏽
Good job ❤
You are really cool😊
Your explanation is so helpful to understand the actions of receptor pharmacology of these medicines. Would you help me to find more infomations about 5-ta 2A- 2C receptors distribution in Mesolimbic and VMPFC, DLPFC, and Insula-amygdala pathways ? And can you tell me the easiest source (illustrated books, videos, or your simple expiation then it w be so beautiful !!) to know more about the different pathways of every neurotransmitters/modulators and its functions in depth.
My questions were little bit confusing . Actually my question are: Can you please tell me about the pathways of mesolimbic, VMPFC, DLPFC, Insula-Amydala: 1). How are they connected? 2). What types of neurotransmitters are acting on or modulating these neuronal networks?. Which networks have5-HT2A-2C receptors as the predominant receptors in these networks.? 4). Can you recommend any illustrated books or videos of lectures that describe these networks? can you please tell me about the pathways of mesolimbic, VMPFC, DLPFC, Insula-Amydala: 1). How are they connected? 2). What types of neurotransmitters are acting on or modulating these neuronal networks?. Which networks have5-HT2A-2C receptors as the predominant receptors in these networks.? 4). Can you recommend any illustrated books or videos of lectures that describe these networks?
Which is a more safest antipsychotic in diabetes for Schizophrenia in between Lurasidone or Aripiprazole ? Plz reply .
Thank you for this video! Ma’am, would you be able to provide the sources for the etiopathogenesis slide please?
Thank you 😊
So helpful
Thank you ❤
Thak you for this really good review
your videos are amazing! im taking my psychiatry clases and these videos have helped me so much. thank you so much for uploading them
Amazing video❤
Okay now how do I get a new brain?
Great
By far, my favorite acne CZcams video! thank you so much and please continue posting videos.
Wonderful lectures! Are you planning a video focusing on PTSD?
Thank you I have a presentation on MDD and I needed to understand the pathophysiology part, thanks a lot!
Myofascial Pain syndrome / myofascial trigger points are the most common source of perstient and chronic pain Myofascial trigger points are a constant source of nociceptive input from the periphery that lead to central sensitization. Myofascial trigger points are discrete PALPABLE hyper irritable nodules in a taut band of skeletal muscle that can only be diagnosed by systematic palpation of the soft tissue by an experienced examiner. Dry needling is unequivocally the most effective treatment to move this common source of nociception.
thank you from Jordan
Well explained but pictures and video is not up to mark
Excellent explanation thx
Thank you for the video, the presentation was great. However i believe you did not explain the pathophysiology well, you mentioned the type 4 H.S reaction as it relates to Psoriasis but never mentioned what could be the specific antigen in this case, you also did not explain why epidermal hyperplasia happens in the first place.
They're not sure about the antigen that triggers psoriasis vulgaris. I've seen LL-37, an antimicrobial peptide produced by keratinocytes, mentioned before as a possible trigger. Then it's the usual: DC to lymf nodes, T-cell activation although I would argue it's both Th1 and Th17, migration to the skin, inflammation. Can't remember which molecule, but probably a T-cell produced interleukin (12, 17, 21 or 22) stimulates keratinocytes to proliferate which causes hyperkeratosis which in turn causes even more LL-37 and cell components which further trigger the immune system
@@Bolcjek Thank you so much
Thank you very much for this very informative review
This is so interesting I had testing done for psychiatric medication and I am an ultra metaboliser. I never knew why opioids made me so sick until this video. Thank you for this understanding! I will even more avoid them.
I thought hydrocodone was equal to morphine, not oxycodone being equal to morphine???
That’s what I’ve seen too.
Several errors in this lecture, and misnomers. I.e. bradycardia due to peripheral effects, where it’s really on vagus nerve stimulation. Moderate tolerance of the heart “muscle” when describing bradycardia
all 3 are similar. It just depends if it's morphine oral or IV, as most often used. Orally it's equal to Hydro, Oxy would be 1.5 that, cuz ur body takes it up better orally. But morphine IV is 3x as potent, so 2 to 3x more potent than Hydro or Oxy too..
Look up Dr Nancy C. Andreasen “the more drugs you've been given, the more brain tissue you lose".
Do we have some references?
This shit destroyed my life
Great video very informative.
This is very good!! Thanks
Amazing >>>>
Great lectures please update playlist
Hello.....I need your help..... please reply
Hello, what is your question?
Thanks for the video. Do you know of a website or podcast that specializes in taking a scientific and evidence based approach to anxiety disorders by looking at specific research papers or interviewing experts in the field? I've thoroughly scanned the internet and podcast world and can't find anything like this strangely.
I'm sorry, I don't know of anything like this!
hi, you covered neurology amazingly. Pls direct us rest of sections of pharmacology if you know them. thank you
THANK YOU
HI I LIVE IN CANADA WE DONT HAVE GOOD DOCTORS IN HERE OK I SUFER TO MUCH ITCH
Very helpful, One of the best videos I've ever watched about the pathophysiology of pain. Thank you
Thank you very much.
really helpful, thank you!!
I'm a pharmaceutical sciences student and have a test tomorrow wich will encompass schizo, parkinsons disease and alzheimer's disease and I Just wanted to thank you because your videos have been really helping me out in my studies. Greetings from Brazil!
You did an amazing job explaining MS drugs !so helpful ! thank you
Hey they give me haldo Dec and they blocked my d2 receptors now I got negative symptoms of schizophrenic when the negative symptoms going go away it been 9 months
Neuro pharmacology of depression is well explained
Fuck I had cyclithimia at first and it progressed to the bipolar 2. I really do not want it to evolve bipolar 1. My hypomanic attacks are very pleasant,I feel a tad more talkative but they only make me feel good. Outside of hypomanic attacks I feel like shit let me have this once or twice a year treat at least. Well if they didnt happened at all it would be pretty good since I could use ritalin for my adhd at least.
Great summary, thanks very much!
Thank you so much for this ,well explained !!
You are awesome❤